Contralateral lymph node metastases in patients with vulvar cancer and unilateral sentinel lymph node metastases

Introduction The risk of contralateral lymph node metastases following unilateral sentinel (SLN) in patients with vulvar cancer(s) remains to be systematically assessed. Material and methods We performed a multicenter, retrospective registry-based study 476 cancer. primary outcome measure was the rate non-SLN case positive SLN. Results Out cancer, 202 received SLN biopsy: 58 144 bilateral. 66 metastatic SLN, 62 (93.9%) lymphadenectomy—18 after 44 bilateral biopsy. In group, 132 were assessed median number 2 (range 1–4) per patient 76 these positive. Lymph node-positivity associated advanced tumor stage, as well vascular space invasion. group inguino-femoral lymphadenectomy, 1004 nodes resected 15 10–29) patient. After full dissection nodes, no found. Conclusions low. Therefore, impact lymphadenectomy on survival should investigated further studies.